
Week 2 College Football Picks for 2025: Expert Advice on Betting Lines and Trends
Expert Bruce Marshall shares his insights on college football betting for the upcoming Week 2 games.
College Football Week 2 Betting Insights
As college football’s Week 2 approaches on Friday, bettors need to evaluate the outcomes of the first week. Notable teams such as Ohio State, TCU, LSU, and Florida State showed strong performances over Labor Day Weekend. Ohio State, LSU, and Florida State will face easier opponents in Week 2, while TCU comes off a dominant win against North Carolina.
Notable Odds for Week 2 Games:
- Oklahoma: -5.5 vs Michigan
- Oregon: -28.5 vs Oklahoma State
- Ole Miss: -10.5 vs Kentucky
Before finalizing your bets, check out the Betting Guide by Bruce Marshall for Week 2. Marshall, known for his expertise, has a history in the sports betting industry, having achieved notable success last season with a record of 64-43.
Key Predictions for the Week:
- Bruce Marshall supports betting on Ole Miss (-10.5) against Kentucky, motivated by revenge after last season’s upset.
“This is a revenge spot for the Rebels after being defeated by 15-point underdog Kentucky. Lane Kiffin has a strong record against the spread in recent Away games.”
For more predictions and insights, follow the full analysis at SportsLine.
Betting Overview for Week 2:
- Friday, Sept. 5:
- James Madison vs. Louisville (-14, 57.5)
- Maryland vs. Northern Illinois (+18.5, 47.5)
- Saturday, Sept. 6:
- Illinois vs. Duke (+3, 49.5)
- Iowa vs. Iowa State (-3, 41.5)
- SMU vs. Baylor (+3, 65.5)
- Texas vs. San Jose State (-36.5, 51.5)
- Clemson vs. Troy (-33.5, 51.5)
- Ole Miss vs. Kentucky (+10.5, 52.5)
- Oregon vs. Oklahoma State (+28.5, 57.5)
- Florida vs. South Florida (+17.5, 54.5)
- Kansas State vs. Army (+17.5, 46.5)
- LSU vs. Louisiana Tech (+37.5, 51.5)
- Arizona State vs. Mississippi State (+7, 58.5)
- Michigan vs. Oklahoma (-5.5, 46.5)
- Alabama vs. UL Monroe (+37.5, 50.5)