College Football Betting Insights for Week 2: Duke and Michigan Highlight Picks for Sept. 6
College Football/Sports

College Football Betting Insights for Week 2: Duke and Michigan Highlight Picks for Sept. 6

A look into the Week 2 college football betting landscape, focusing on key picks involving Michigan and Duke.

After a thrilling opening weekend, the Week 2 college football schedule features a single Top 25 matchup.

The No. 18 Oklahoma Sooners will host the No. 15 Michigan Wolverines at OU Memorial Stadium on Saturday at 7:30 p.m. ET. The Sooners opened their season with a 35-3 victory against Illinois State, while Michigan decisively beat New Mexico 34-17. The latest Week 2 college football odds show the Sooners as 5.5-point favorites with an over/under set at 44.5 points. SportsLine’s model favors Michigan, which has a strong record of 12-3 in its last 15 away games.

Key Betting Insights:

  • The model supports Michigan (+5.5) against Oklahoma (-110).
  • Duke (+3) is projected to cover at home against Illinois (-110).
  • Expect over 47.5 points in the matchup between Vanderbilt and Virginia Tech (-110).

Week 2 Betting Picks:

  • Michigan vs. Oklahoma: Michigan +5.5
  • Duke vs. Illinois: Duke +3
  • Vanderbilt vs. Virginia Tech: Over 47.5 points

Combining these selections into a parlay would yield a payout of +596 (a risk of $100 to win $596).

Want more College Football Insights?

Explore additional picks from SportsLine’s reliable model, which has simulated over 10,000 games.

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