Game Overview

The Denver Broncos will face off against the Tennessee Titans as the 2025 NFL season commences. The Broncos had a successful 2024 season, finishing 10-7 and making it to the playoffs. In contrast, the Titans struggled, posting a 3-14 record and securing Cameron Ward as their first overall pick in the 2025 NFL Draft.

Kickoff is slated for 4:05 PM ET at Empower Field at Mile High in Denver. The current betting odds favor the Broncos by 8.5 points, with a total points over/under set at 42.5. Bets indicate the Broncos are -455 favorites to win, while the Titans are positioned as +351 underdogs.

Prior to making any betting decisions, refer to the picks provided by the SportsLine projection model, which has demonstrated successful performance over time. The model has logged over $7,000 in profit for $100 bettors on its top-rated NFL picks.

Key Betting Insights

• Broncos -8.5 The Broncos have shown strength against the spread, maintaining an 8-0 record as favorites last season, and they were 6-0 as home favorites. With Cam Ward making his debut in a challenging away venue, the Broncos are expected to perform well.

• Over 42.5 Total Points Last year, Denver was among the top performing scoring offenses, suggesting a strong potential for scoring. The addition of new players this offseason has further bolstered their offensive lineup, while the Titans also possess key offensive threats.

For more comprehensive predictions and expert insights, check the full analysis linked within this article.