The Atlanta Falcons aim to claim their third consecutive victory as they face the hindered San Francisco 49ers in this week’s Sunday Night Football matchup. The 49ers are grappling with injuries, notably losing linebacker Fred Warner to season-ending surgery, while they contend with a growing roster of players in and out of the lineup.

Kickoff is scheduled for 8:20 p.m. ET at Levi’s Stadium in Santa Clara, California. The 49ers currently hold the historical advantage in the rivalry, leading the all-time series 48-33-1. San Francisco is favored by 1 point in the latest odds, with an over/under for total points at 46.5.

Why the 49ers can cover:

• Christian McCaffrey shines as both the leading rusher and receiver, boasting remarkable stats this season of 336 rushing yards and 444 receiving yards with four touchdowns combined.

Why the Falcons can cover:

• Second-year quarterback Michael Penix Jr. has demonstrated his abilities, throwing for 1,168 yards along with several decisive performances enhancing his team’s chances.

This matchup promises excitement as both teams seek victory against the odds.