The 2025-26 college basketball schedule kicks off on November 7, featuring nine games with ranked teams. One of the highlights is the clash between No. 19 Kansas and No. 25 North Carolina, marking Kansas’s first-ever visit to Chapel Hill, where they will face the Tar Heels, who are favorited by 2.5 points. The expected over/under for the match is set at 157.5.

Other notable games on the betting lines include:

• Georgetown vs. Maryland (-4.5)
• Valparaiso vs. Kentucky (-32.5)
• Detroit vs. Notre Dame (-21.5)

Before making any wagers, ensure to check the recommendations and predictions from SportsLine’s trusted computer model, which has accurately simulated these matchups 10,000 times. This model has systematically yielded a return of over $2,200 in profit for $100 players based on top-rated picks over the last three seasons.

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Top Picks for Friday, November 7

Following 10,000 simulations, the model supports George Mason (-11.5) to beat Winthrop, scheduled for a 7 p.m. ET start. George Mason opened its season with a decisive 70-46 victory against Wofford, propelled by junior guard Kory Mincy, who scored 18 points and made six assists.

Keep an eye on the Kansas vs. North Carolina matchup, as this game reportedly exceeds a 60% success rate!

For comprehensive betting guidance, revisit SportsLine for detailed information and recommendations on college basketball bets.