Injury Update for NFL Week 15: Key Players Impacting Bettors

As we approach Week 15 of the 2025 NFL season, injuries continue to affect several teams. With playoffs around the corner, teams are evaluating player fitness while aiming for a strong finish to the season. Noteworthy injuries for bettors this week include:

Ravens vs Bengals (1 p.m. ET)

CIN WR Tee Higgins (concussion, out)

Star receiver Tee Higgins will not play following his second concussion this season, impacting the Bengals’ offensive strategy.

Raiders vs Eagles (1 p.m. ET)

LV QB Geno Smith (right shoulder and back, out)
PHI OT Lane Johnson (foot, out)

Kenny Pickett starts in place of the injured Geno Smith, while the Eagles will miss star tackle Lane Johnson.

Cardinals vs Texans (1 p.m. ET)

AZ WR Marvin Harrison Jr. (heel, out)
HOU RB Nick Chubb (ribs, questionable)

Marvin Harrison Jr. is sidelined as the Cardinals struggle with losses, while Chubb’s availability remains uncertain.

Chargers vs Chiefs (1 p.m. ET)

LAC WR Quentin Johnston (groin, questionable)
KC WR Hollywood Brown (personal, out)

Both teams face substantial issues in their receiver lines, impacting game plans and betting lines.

Bills vs Patriots (1 p.m. ET)

No major injuries

This matchup represents a clash between two strong AFC East teams, with Buffalo slightly favored.

Jets vs Jaguars (1 p.m. ET)

NYJ QB Tyrod Taylor (groin, out)
NYJ QB Justin Fields (knee, out)
NYJ TE Mason Taylor (neck, out)

Brady Cook will make his start as the Jets contend with multiple key player absences.

Commanders vs Giants (1 p.m. ET)

WASH QB Jayden Daniels (left elbow, out)
WASH WR Deebo Samuel (illness, questionable)

With Daniels out again, Marcus Mariota steps up under center.

Browns vs Bears (1 p.m. ET)

CLE TE David Njoku (knee, out)
CLE RB Dylan Sampson (calf and hand, out)
CLE CB Denzel Ward (calf, out)

The Browns will take the field missing numerous key players against the resurgent Bears.

Panthers vs Saints (4:25 p.m. ET)

NO RB Alvin Kamara (knee and ankle, out)

Kamara’s absence greatly affects the Saints’ ground attack against the Panthers.

Lions vs Rams (4:25 p.m. ET)

DET S Brian Branch and Kerby Joseph (out)
LAR WR Davante Adams (hamstring, questionable)

Both teams are facing critical injuries as they vie for institutional playoff positions.

Colts vs Seahawks (4:25 p.m. ET)

IND QB Riley Leonard (knee, will be active)
IND CB Sauce Gardner (calf, out)

The Colts have a critical game to contend with, and fans await the return of Leonard.

Packers vs Broncos (4:25 p.m. ET)

GB RB Josh Jacobs (knee, questionable)

Jacobs’ availability could be a game-changer for the Packers.

Titans vs 49ers (4:25 p.m. ET)

SF RB Christian McCaffrey (back, questionable)

McCaffrey’s injury status remains a significant factor leading into this matchup.

Vikings vs Cowboys (8:20 p.m. ET)

DAL TE Jake Ferguson (calf, questionable)

Strength in depth will be tested as the teams prepare to meet.

Dolphins vs Steelers (8:15 p.m. ET)

PITT LB T.J. Watt (lung, out)

Watt’s absence is critical for the Steelers’ defensive strategy as they face the Dolphins.