The 2025 NFL Christmas Day tripleheader starts with Cowboys vs. Commanders at 1 p.m. ET, followed by Lions vs. Vikings at 4:30 p.m. ET, and wraps up with Chiefs vs. Broncos at 8:15 p.m. ET. Despite significant quarterback injuries sideling notable players like Patrick Mahomes and J.J. McCarthy, the lineup still offers several excellent choices for DFS formats.

Stars like Dak Prescott, CeeDee Lamb, Jahmyr Gibbs, Justin Jefferson, and Travis Kelce are among the top picks for your daily Fantasy football lineups.

However, due to the high price tags of these elite players, balancing your roster with more budget-friendly options is essential. The absence of key QBs might also allow Chris Oladokun or Max Brosmer to emerge as viable selections for your Christmas NFL DFS lineups.

Before making any decisions on your NFL DFS picks for Christmas, be sure to check out the latest advice, strategies, and stacks from Mike McClure at SportsLine.