Duke Blue Devils vs. Louisville Cardinals Preview

On January 6, 2026, the Duke Blue Devils will take on the Louisville Cardinals in their third ACC game of the season at 7 p.m. ET from the KFC Yum! Center in Louisville, KY.

• Current Records:
  • Duke: 13-1 (2-0 ACC)
  • Louisville: 11-3 (1-1 ACC)

Duke has been successful in its last games, defeating Florida State with a close score of 91-87. Louisville, on the other hand, suffered a narrow defeat against Stanford (80-76) in its previous outing. Duke holds an impressive record against Louisville, having won their last seven encounters.

Betting Odds

• Louisville: -1.5 favorites
• Over/Under: 161.5 points

Before placing any bets, make sure to leverage insights from the SportsLine Projection Model that accurately simulates every game.

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Conclusion

The advanced model forecasts a total of 158 points for this matchup, suggesting a lean towards the under. With Duke’s defense and Louisville’s recent performance considered, this game is set to be thrilling.

Follow the outcome and make your predictions wisely!