The 2025 NCAA Tournament is poised to kick off, with many surprises expected. The tournament will begin on Thursday, March 20, 2025.

Top Upsets and Picks

One intriguing upset pick involves the First Four winner between North Carolina and San Diego State, expected to take down No. 6 Ole Miss. Both teams are entering the tournament as 11 seeds, making this matchup one to watch. Fans can expect Creighton to potentially overcome Louisville in another key 8-9 matchup.

Making Predictions

For comprehensive insights on the entire bracket, check out the model that has accurately predicted numerous upsets in past tournaments. It has successfully forecasted 24 first-round surprises since it started running simulations in 2016. Active participants looking to place their bets or make projections should closely follow updates from SportsLine.